October 1, 2006Annals of the New York Academy of Sciences
The Integration of Spontaneous Intracellular Ca²⁺ Cycling and Surface Membrane Ion Channel Activation Entrains Normal Automaticity in Cells of the Heart's Pacemaker
Population
Sinoatrial nodal cells (SANC)
Design
Review
Authors
Discussion
Loading...
Member takes
Implication
Advances coupled-clock model of sinoatrial pacemaking; leaves open clinical translation to arrhythmia therapies.
Structured PICO
P
Population
Sinoatrial nodal cells (SANC)
The integration of the intracellular Ca2+ clock and surface membrane ion channels is the formal cause of basal and reserve rhythms in sinoatrial nodal cells.
Cite This Study
Lakatta et al. (2006) studied this question.