August 1, 1995ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)
Alterations in intracellular cations and cell membrane ATPase activity in patients with malignant hypertension
Why the study?
Are cellular cation concentrations and cell membrane ATPase activity altered in patients with malignant hypertension compared to essential hypertensive and normotensive subjects?
Population
16 black patients with malignant hypertension, and age- and sex-matched essential hypertensive and…
Design
Case-control
Authors
Discussion
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Implication
Altered cellular cations associate with malignant hypertension severity; hypothesis-generating and should not yet change practice.
Structured PICO
Are cellular cation concentrations and cell membrane ATPase activity altered in patients with malignant hypertension compared to essential hypertensive and normotensive subjects?
P
Population
16 black patients with malignant hypertension, and age- and sex-matched essential hypertensive and normotensive subjects
C
Comparator
Age- and sex-matched essential hypertensive and normotensive subjects
O
Outcome
Intracellular concentrations of calcium, magnesium, sodium, and potassium, and cell membrane Na,K-ATPase, Ca-ATPase, and Mg-ATPase activities in platelets and erythrocytessurrogate
Malignant hypertension is associated with more pronounced alterations in cellular cation concentrations and cell membrane ATPase activity compared to benign essential hypertension.
Cite This Study
Touyz et al. (1995) studied this question.