Population
Saponin-treated skinned muscles from the myometrium of 21-day pregnant rats
Design
Preclinical
Authors
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Extends InsP3-Ca2+ release to pregnant rat myometrium; leaves open translation to human uterine or vascular physiology.
Inositol 1,4,5-trisphosphate (InsP3) releases calcium from intracellular stores in pregnant rat myometrium, similar to mechanisms proposed in vascular smooth muscle.
Kanmura et al. (1988) studied this question.
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