Key result
Acetylcholine and angiotensin II induced transient contractions in rat myometrial strips in Ca2+-free medium, indicating an intracellular Ca2+ store independent of plasma membrane depolarization.
Population
Rat myometrial strips perfused in Ca2+-free EGTA-containing solutions
Design
Preclinical
Authors
Loading...
May inform models of uterine contractility; leaves open translation to human myometrial function.
Rat myometrial cells possess an intracellular Ca2+ store sensitive to acetylcholine and angiotensin II that is independent of plasma membrane depolarization.
Lalanne et al. (1984) studied Rat uterine smooth muscle physiology. Acetylcholine and Angiotensin II was evaluated on Transient contractions and depolarizations. Acetylcholine and angiotensin II induced transient contractions in rat myometrial strips in Ca2+-free medium, indicating an intracellular Ca2+ store independent of plasma membrane depolarization.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: