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July 1, 1937Annals of Internal Medicine

Studies on Experimental Hypertension

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Population

dogs and monkeys

Design

Preclinical

Follow-up

more than five years (in some dogs)

Authors

HGHarry GoldblattFood and Agriculture Organization of the United Nations

Discussion

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Implication

Supports experimental models of renovascular hypertension; leaves open translation to human disease and therapy.

Structured PICO

P
Population
dogs and monkeys
I
Intervention
constriction of the main renal arteries using a special silver clamp
O
Outcome
production of persistent hypertensionsurrogate

Constriction of the main renal arteries using a silver clamp produces persistent experimental hypertension in animal models, with severity dependent on the degree of constriction.

Cite This Study

Harry Goldblatt (1937) studied this question.

synapsesocial.com/papers/6a7d15682935e92dbc775445https://doi.org/10.7326/0003-4819-11-1-69
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Nature of Peripheral Resistance in Arterial Hypertension1936 · 12 citations
  2. 2PRESSOR SUBSTANCES FROM THE BODY FLUIDS OF MAN IN HEALTH AND DISEASE1935 · 33 citations