Population
Pig coronary artery endothelium and smooth muscle (cultured cells and intact artery rings)
Comparison
Peroxide exposure vs Comparison between endothelial cells and smooth…
Design
Preclinical
Authors
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May preserve endothelial function in oxidative stress; leaves open relevance to human coronary ischemia-reperfusion.
Coronary artery endothelium exhibits greater resistance to peroxide-induced SERCA pump dysfunction compared to smooth muscle, potentially preserving endothelial function during oxidative stress such as ischemia-reperfusion.
Grover et al. (1997) studied this question.
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