Why the study?
Does increased cardiac output contribute to the development of experimental renal hypertension in dogs?
Population
Dogs (experimental model of renal hypertension)
Comparison
Production of hypertension by the cellophane… vs Baseline measurements
Design
Preclinical
Follow-up
Up to 4 weeks after nephrectomy
Authors
Loading...
Early cardiac output rise may initiate experimental renal hypertension; extends pathogenesis insights but leaves open human translation.
Does increased cardiac output contribute to the development of experimental renal hypertension in dogs?
In an experimental dog model, an initial increase in cardiac output precedes the rise in arterial pressure, suggesting it plays a contributory role in the development of renal hypertension.
Ferrario et al. (1970) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: