Defining myocardial fiber bundle architecture in atrial digital twins

Figures

• 

  Fig. A.1.. Atrial surface labeling procedure performed to impose the boundary conditions for the atrial LDRBM (presented in Section 2.1): (1.) crafting the LA (in red) and RA (in blue) rings; (2.) extracting LA (red), RA (blue) endocardium and atrial epicardium (gray); (3a., 3b.) LA and RA point selection procedures applied to compute shortest distance path employed to perform the endocardial bands labeling; (4a., 4b.) LA and RA point selection procedures applied to compute shortest distance path employed to perform the epicardial bands labeling; (5) annulus splitting (anterior, posterior, lateral and septal) for MV and TV. On the right, the final result of the labeling procedure applied to Geo 7 of the DTMRI dataset.

• 

  Fig. C.1.. IC (black), PM (dark blue) and CT (light blue) bundles extraction performed by the bi-atrial LDRBM for DTMRI geometries. IC = Interatrial-Connections, PM = Pectinate Muscles, CT = Crista Terminalis.

• 

  Fig. C.2.. Histograms displaying the measured alpha angle (with respect to LDRBM coordinate axis system) across the eight DTMRI geometries in LA bundles (MV, LAS, BB) in the sub-epicardial (red) and sub-endocardial (blue) layers.

• 

  Fig. C.3.. Histograms displaying the measured alpha angle (with respect to LDRBM coordinate axis system) across the eight DTMRI geometries in LA bundles (LIPV, LSPV, LC) in the sub-epicardial (red) and sub-endocardial (blue) layers.

• 

  Fig. C.4.. Histograms displaying the measured alpha angle (with respect to LDRBM coordinate axis system) across the eight DTMRI geometries in LA bundles (LAR, LAW-top, LAW-bot) in the sub-epicardial (red) and sub-endocardial (blue) layers.

• 

  Fig. C.5.. Histograms displaying the measured alpha angle (with respect to LDRBM coordinate axis system) across the eight DTMRI geometries in LA bundles (RIPV, RSPV, RC) in the sub-epicardial (red) and sub-endocardial (blue) layers.

• 

  Fig. C.6.. Histograms displaying the measured alpha angle (with respect to LDRBM coordinate axis system) across the eight DTMRI geometries in LA bundles (LAA, LSW, LLW) in the sub-epicardial (red) and sub-endocardial (blue) layers.

• 

  Fig. C.7.. Histograms displaying the measured alpha angle (with respect to LDRBM coordinate axis system) across the eight DTMRI geometries in RA bundles (TV, ICV, SCV) in the sub-epicardial (red) and sub-endocardial (blue) layers.

• 

  Fig. C.8.. Histograms displaying the measured alpha angle (with respect to LDRBM coordinate axis system) across the eight DTMRI geometries in RA bundles (IB, RAA, CSM) in the sub-epicardial (red) and sub-endocardial (blue) layers.

• 

  Fig. C.9.. Histograms displaying the measured alpha angle (with respect to LDRBM coordinate axis system) across the eight DTMRI geometries in RA bundles (RAS, RAW, RPW) in the sub-epicardial (red) and sub-endocardial (blue) layers.

• 

  Fig. C.10.. Histograms displaying the measured alpha angle (with respect to LDRBM coordinate axis system) across the eight DTMRI geometries in RLW bundle in the sub-epicardial (red) and sub-endocardial (blue) layers. CT, PM and inter-atrial connections (FO-IC, BB-IC) depicted in black.

• 

  Fig. C.11.. Circular histograms of dominant angle within LA bundles: sub-endocardium (blue), sub-epicardium (red) and inter-atrial connections (black) across eight DTMRI dataset geometries. Mean angle represented by dotted line. Resultant mean vector depicted in black, with length indicative of angular variance. Corresponding SD values for each bundle shown in table at bottom right corner, with SD color-coded on a scale from minimal (12°) to maximal (37°).