Why the study?
What is the long-term clinical outcome of mothers and children with autoantibody-associated congenital heart block?
Population
55 children with isolated congenital heart block, their 52 mothers, and 5 other women currently carrying…
Design
Cohort
Follow-up
1 week to 20 years (median, 3.7 years)
Authors
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Supports monitoring asymptomatic mothers and affected neonates; leaves open optimal screening and intervention strategies.
What is the long-term clinical outcome of mothers and children with autoantibody-associated congenital heart block?
In autoantibody-associated congenital heart block, asymptomatic mothers frequently develop rheumatic disease over time, and affected children face high early neonatal mortality and a high rate of pacemaker implantation.
Jonathan Waltuck (1994) studied this question.
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