Natural products in drug discovery: advances and opportunities
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Overview
Review reveals technological breakthroughs in natural product drug discovery pipelines, highlighting renewed opportunities to combat rising antimicrobial resistance.
Key Points
- Summarize recent technological innovations that overcome historical bottlenecks in natural product research and highlight key therapeutic opportunities.
- Synthesized historical trends regarding the decline and renewed viability of natural products in pharmaceutical development.
- Evaluated cutting-edge developments across analytical instrumentation, microbial culturing techniques, and genome mining strategies.
- Modern analytical and genomic technologies directly resolve legacy obstacles in compound isolation, high-throughput screening, and chemical optimization.
- Culturing and genetic engineering breakthroughs unlock previously inaccessible microbial biodiversity to furnish novel leads against antimicrobial resistance.
Cite This Study
Atanasov et al. (2021) studied this question.