Why the study?
Does high calcium concentration improve the recovery of contractile tension in frog heart ventricular muscle strips following anoxia at low pH?
Population
Heart ventricular muscle strips from the frog, Rana temporaria
Comparison
High calcium concentration during anoxia at pH… vs Physiological solution at pH 7.6 or pH 6.6 with…
Design
Preclinical
Follow-up
Up to 1 hour of recovery following 60 min of anoxia
Authors
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High calcium may aid anoxic recovery in frog myocardium; leaves open translation to mammalian or clinical ischemia-reperfusion.
Does high calcium concentration improve the recovery of contractile tension in frog heart ventricular muscle strips following anoxia at low pH?
High calcium concentrations can overcome the detrimental effects of low pH on the recovery of contractile tension in frog ventricular muscle following anoxia.
Lagerstrand et al. (1980) studied this question.
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