Population
Rats (Sprague-Dawley and Brattleboro) and rabbits
Comparison
Intravenous infusions of vasopressin vs Intravenous infusions of phenylephrine
Design
Preclinical
Authors
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Species differences in vasopressin baroreflex effects caution against cross-species extrapolation; leaves open translation to human sympathetic regulation.
Intravenous vasopressin facilitates baroreflex inhibition of lumbar sympathetic nerve activity in rabbits but not in rats, highlighting a species-specific difference in central baroreflex modulation.
Sharabi et al. (1985) studied this question.
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