September 1, 1986AJP Heart and Circulatory Physiology

Sites at which vasopressin facilitates baroreflex inhibition of lumbar sympathetic nerve activity

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Population

Anesthetized rabbits

Comparison

Intravenous infusion of vasopressin vs Phenylephrine

Design

Preclinical

Authors

GGG. B. GuoUniversity of Iowa PSPhillip G. SchmidSt Bartholomew's Hospital FAFrançois M. AbboudGeneral Cardiology

Discussion

Member takes

Implication

Hypothesis-generating for vasopressin's baroreflex facilitation; should not yet alter clinical vasopressor selection.

Structured PICO

Population

Anesthetized rabbits

Intervention

Intravenous infusion of vasopressin (16-32 mU X kg-1 X min-1)

Comparator

Phenylephrine

Outcome

Inhibition of lumbar sympathetic nerve activity and afferent activity of the aortic depressor nervesurrogate

Circulating vasopressin facilitates baroreflex inhibition of sympathetic nerve activity through both central nervous system actions and effects on arterial baroreceptors.

Cite This Study

Guo et al. (1986) studied this question.

synapsesocial.com/papers/6a8382316524aee222604e15 https://doi.org/10.1152/ajpheart.1986.251.3.h644

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Sites at which vasopressin facilitates baroreflex inhibition of lumbar sympathetic nerve activity

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Sites at which vasopressin facilitates baroreflex inhibition of lumbar sympathetic nerve activity

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider