June 1, 1997AJP Heart and Circulatory Physiology
Left-to-right systolic and diastolic ventricular interactions are dependent on right ventricular volume
Why the study?
Does right ventricular volume modulate left-to-right ventricular interaction in an isolated canine heart model?
Population
Isolated cross-perfused canine heart preparation
Comparison
Increased right ventricular volume vs Baseline right ventricular volume
Design
Preclinical
Authors
Discussion
Loading...
Member takes
Implication
RV volume must be accounted for when interpreting ventricular interactions; leaves open translation beyond isolated canine models.
Structured PICO
Does right ventricular volume modulate left-to-right ventricular interaction in an isolated canine heart model?
P
Population
Isolated cross-perfused canine heart preparation
I
Intervention
Increased right ventricular volume
C
Comparator
Baseline right ventricular volume
O
Outcome
Left-to-right systolic and diastolic gainsurrogate
Left-to-right systolic and diastolic ventricular interactions are dependent on right ventricular volume, highlighting the need to account for loading conditions when interpreting these interactions.
Cite This Study
Dickstein et al. (1997) studied this question.