Why the study?
Does the mu-antibody capture ELISA test effectively diagnose recent coxsackie B virus infections in patients with myo/pericarditis and other symptoms?
Population
760 patients with suspected coxsackie B virus infections and 304 healthy adult controls.
Comparison
mu-antibody capture ELISA test for the detection… vs Healthy adult controls
Design
Cross-sectional
Authors
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CBV IgM positivity may support recent infection in myo/pericarditis; leaves open ELISA diagnostic utility pending prospective validation.
Does the mu-antibody capture ELISA test effectively diagnose recent coxsackie B virus infections in patients with myo/pericarditis and other symptoms?
The mu-antibody capture ELISA test for CBV-specific IgM, combined with neutralization tests, is a useful screening tool for diagnosing recent coxsackie B virus infections in patients with myo/pericarditis.
McCartney et al. (1986) studied this question.
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