Why the study?
Does insulin administration restore impaired arachidonic acid metabolism of platelets and vessel walls in STZ-induced diabetic rats?
Does insulin administration restore impaired arachidonic acid metabolism of platelets and vessel walls in STZ-induced diabetic rats?
Insulin administration restores the balance between vascular PGI2 and platelet TXA2 in experimental diabetic rats, suggesting a mechanism for preventing diabetic vascular injury.
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Suggests vascular protection via insulin in diabetic models; leaves open translation to human complications.
RIN et al. (1985) studied this question.
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