Why the study?
Does plasma PGI2-regenerating activity differ between diabetic patients and normal volunteers?
Does plasma PGI2-regenerating activity differ between diabetic patients and normal volunteers?
Diabetic patients exhibit reduced plasma PGI2-regenerating activity, which is further decreased in those with retinopathy and may contribute to microvascular and thrombotic complications.
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May signal heightened vascular risk in diabetes; hypothesis-generating for microvascular complications and requires prospective validation.
Sensaki et al. (1984) studied this question.
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