Studies in Clinical Shock and Hypotension
Why the study?
Does rapid infusion of dextran improve hemodynamics in patients with nonhemorrhagic shock or hypotension?
Population
31 patients with nonhemorrhagic shock or hypotension of diverse etiologies accompanied by low cardiac output…
Design
Case_series
Authors
Discussion
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Implication
Case reports should not change shock management; randomized trials needed to confirm hemodynamic effects.
Structured PICO
Does rapid infusion of dextran improve hemodynamics in patients with nonhemorrhagic shock or hypotension?
P
Population
31 patients with nonhemorrhagic shock or hypotension of diverse etiologies accompanied by low cardiac output and normal or low right atrial pressure
I
Intervention
Rapid infusion of dextran (low molecular weight or clinical dextran)
O
Outcome
Hemodynamic response (cardiac output, blood pressure, right atrial pressure, peripheral vascular resistance)surrogate
Rapid infusion of dextran effectively corrects hemodynamics in a subset of patients with nonhemorrhagic shock and normal or low central venous pressure.
Cite This Study
Cohn et al. (1967) studied this question.