Key result
Among older Black adults, a doubling of serum adiponectin was associated with a higher risk of incident coronary heart disease (HR 1.37; 95% CI 1.01-1.87).
Why the study?
Are serum adiponectin levels associated with prevalent and incident coronary heart disease in older Black and White adults?
Population
3,075 well-functioning Black and White adults aged 70 to 79 years enrolled in the Health, Aging, and Body…
Design
Cohort
Follow-up
6 years
Authors
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Should not yet alter risk assessment in older Black adults; extends race-specific adiponectin observations and leaves open prospective validation.
Cohort (n=3,075)
Yes
Are serum adiponectin levels associated with prevalent and incident coronary heart disease in older Black and White adults?
Hazard Ratio: 1.37 (95% CI 1.01–1.87)
High circulating adiponectin concentrations are associated with a higher risk of coronary heart disease in older Black adults, contrasting with the inverse association seen in White adults.
Kanaya et al. (2006) conducted a cohort in Coronary heart disease (n=3,075). Serum adiponectin was evaluated on Incident CHD (hospitalized myocardial infarction or CHD death) (HR 1.37, 95% CI 1.01-1.87). Among older Black adults, a doubling of serum adiponectin was associated with a higher risk of incident coronary heart disease (HR 1.37; 95% CI 1.01-1.87).
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