Why the study?
Do newer antihypertensive agents reduce ventricular fibrosis and improve coronary hemodynamics in hypertensive heart disease?
Population
Hypertensive patients and spontaneously hypertensive rats
Design
Review
Authors
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Should not yet change antihypertensive selection; leaves open clinical outcome benefits in hypertensive heart disease.
Do newer antihypertensive agents reduce ventricular fibrosis and improve coronary hemodynamics in hypertensive heart disease?
Newer antihypertensive agents may mitigate the risk of diastolic heart failure in hypertensive heart disease by reducing ventricular fibrosis and improving coronary hemodynamics.
E D Frohlich (2001) studied this question.
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