Population
Male Sprague-Dawley rats (225 to 250 g)
Comparison
Intravenous infusion of porcine renin at low or… vs 0.9% NaCl infusion
Design
Preclinical
Follow-up
5 days
Authors
Loading...
Does not inform clinical hypertension management; leaves open tissue-specific angiotensinogen regulation beyond Ang II in humans.
Renin infusion differentially regulates angiotensinogen gene expression across various tissues through mechanisms beyond circulating angiotensin II levels.
Milsted et al. (1996) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: