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March 14, 2019Birth Defects Research

Fetal aortic valvuloplasty to prevent progression to hypoplastic left heart syndrome in utero

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Key result

Fetal aortic valvuloplasty is a fetal cardiac intervention that may be performed to prevent progression to hypoplastic left heart syndrome in utero.

Why the study?

Advances in fetal echocardiography have enabled fetal cardiac intervention, such as fetal aortic valvuloplasty, to prevent progression to hypoplastic left heart syndrome in utero.

Design

Review

Authors

MCMatthew A. CrystalPresbyterian HospitalLFLindsay R. FreudPediatric / Congenital Cardiology

Discussion

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Implication

May offer intervention option for select fetal aortic stenosis; leaves open need for prospective trials before clinical adoption.

Structured PICO

P
Population
Fetuses with congenital heart disease at risk of progression to hypoplastic left heart syndrome
I
Intervention
Fetal aortic valvuloplasty (FAV)

Fetal aortic valvuloplasty is a fetal cardiac intervention that may prevent the progression of select congenital heart defects to hypoplastic left heart syndrome in utero.

Cite This Study

Crystal et al. (2019) conducted a review in Hypoplastic left heart syndrome. Fetal aortic valvuloplasty was evaluated. Fetal aortic valvuloplasty is a fetal cardiac intervention that may be performed to prevent progression to hypoplastic left heart syndrome in utero.

synapsesocial.com/papers/6a7da90b33dcb27c99cb528chttps://doi.org/10.1002/bdr2.1478

Topics

Congenital heart disease adults
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Functional state following the Fontan procedure2009 · 32 citations
  2. 2Changes in left heart hemodynamics after technically successful in‐utero aortic valvuloplasty2007 · 96 citations
  3. 3Predictors of Technical Success and Postnatal Biventricular Outcome After In Utero Aortic Valvuloplasty for Aortic Stenosis With Evolving Hypoplastic Left Heart Syndrome2009 · 313 citations
  4. 4Early hemodynamic changes after fetal aortic stenosis valvuloplasty predict biventricular circulation at birth2018 · 37 citations
  5. 5Balloon dilatation of the aortic valve in the fetus: a report of two cases.1991 · 251 citations