Why the study?
Does dopamine directly stimulate renin release in an in vitro rat kidney slice model?
Population
in vitro rat kidney slice system
Design
Preclinical
Authors
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Suggests beta-adrenergic mediation of dopamine effects on renin in vitro; leaves open relevance to human physiology.
Does dopamine directly stimulate renin release in an in vitro rat kidney slice model?
Dopamine directly stimulates renin release in vitro through an agonistic effect on the juxtaglomerular beta receptor rather than a specific dopaminergic receptor.
Henry et al. (1977) studied this question.
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