Key result
Antiviral agents targeting viral polymerases represent a valid and favorable molecular strategy for the development of therapies against HCV, herpesviruses, HIV, HBV, and influenza virus.
Design
Review
Authors
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Supports polymerase targeting for antivirals across viruses; hypothesis-generating and should not yet change practice.
Viral polymerases are valid molecular targets for the design of effective antiviral drugs across multiple virus families.
Tsai et al. (2006) conducted a review in Viral infections (HCV, herpesviruses, HIV, HBV, influenza virus). Antiviral agents targeting viral polymerases was evaluated. Antiviral agents targeting viral polymerases represent a valid and favorable molecular strategy for the development of therapies against HCV, herpesviruses, HIV, HBV, and influenza virus.
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