What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Healthy subjects (n=136). Intervention: Transthoracic coronary flow reserve (CFR). Primary outcome: Correlation between transthoracic coronary flow reserve (CFR) and surrogates of coronary atherosclerosis (r = -0.388, p=< 0.01).

October 26, 2006Echocardiography

Interrelationship Between Noninvasive Predictors of Atherosclerosis: Transthoracic Coronary Flow Reserve, Flow‐Mediated Dilation, Carotid Intima‐Media Thickness, Aortic Stiffness, Aortic Distensibility, Elastic Modulus, and Brachial Artery Diameter

Q: What are the key findings of this study?

Transthoracic coronary flow reserve significantly correlated with noninvasive predictors of atherosclerosis, including carotid IMT (r=-0.388, P<0.01) and brachial EDD (r=0.302, P<0.01).

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Key result

Transthoracic coronary flow reserve significantly correlated with noninvasive predictors of atherosclerosis, including carotid IMT (r=-0.388, P<0.01) and brachial EDD (r=0.302, P<0.01).

Population

136 healthy subjects free of coronary risk factors, mean age 39.9 +/- 7.3 years.

Design

Cross-sectional

Authors

HGHakan Güllü DEDoğan Erdoğan MÇMustafa Çalışkan

Discussion

Member takes

Overview

Supports noninvasive coronary flow reserve assessment in atherosclerosis research; leaves open its clinical adoption pending prospective validation.

Study Design

Type

Cross-Sectional (n=136)

Structured PICO

Population

136 healthy subjects (mean age 39.9 years) free of coronary risk factors.

Exposure

Measurement of transthoracic coronary flow reserve (CFR) and other noninvasive predictors of atherosclerosis (aortic stiffness index, aortic distensibility, aortic elastic modulus, brachial artery vasomotion, carotid IMT)

Outcome

Correlation between transthoracic coronary flow reserve (CFR) and well-established surrogates of coronary atherosclerosissurrogate

Main Result

Effect estimate: r = -0.388

p-value: p=< 0.01

Transthoracic coronary flow reserve correlates significantly with established noninvasive predictors of atherosclerosis, suggesting its potential utility as a surrogate marker for coronary atherosclerosis.

Cite This Study

Güllü et al. (2006) conducted a cross-sectional in Healthy subjects (n=136). Transthoracic coronary flow reserve (CFR) was evaluated on Correlation between transthoracic coronary flow reserve (CFR) and surrogates of coronary atherosclerosis (r = -0.388, p=< 0.01). Transthoracic coronary flow reserve significantly correlated with noninvasive predictors of atherosclerosis, including carotid IMT (r=-0.388, P<0.01) and brachial EDD (r=0.302, P<0.01).

synapsesocial.com/papers/6a7dbe261693de70af99aa63 https://doi.org/10.1111/j.1540-8175.2006.00342.x

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October 26, 2006Echocardiography

Interrelationship Between Noninvasive Predictors of Atherosclerosis: Transthoracic Coronary Flow Reserve, Flow‐Mediated Dilation, Carotid Intima‐Media Thickness, Aortic Stiffness, Aortic Distensibility, Elastic Modulus, and Brachial Artery Diameter

View Full Paper

Ask AI

Bookmark

Key result

Transthoracic coronary flow reserve significantly correlated with noninvasive predictors of atherosclerosis, including carotid IMT (r=-0.388, P<0.01) and brachial EDD (r=0.302, P<0.01).

Population

136 healthy subjects free of coronary risk factors, mean age 39.9 +/- 7.3 years.

Design

Cross-sectional

Authors

HGHakan Güllü DEDoğan Erdoğan MÇMustafa Çalışkan

Discussion

Member takes

Overview

Supports noninvasive coronary flow reserve assessment in atherosclerosis research; leaves open its clinical adoption pending prospective validation.

Study Design

Type

Cross-Sectional (n=136)

Structured PICO

Population

136 healthy subjects (mean age 39.9 years) free of coronary risk factors.

Exposure

Outcome

Correlation between transthoracic coronary flow reserve (CFR) and well-established surrogates of coronary atherosclerosissurrogate

Main Result

Effect estimate: r = -0.388

p-value: p=< 0.01

Cite This Study

synapsesocial.com/papers/6a7dbe261693de70af99aa63 https://doi.org/10.1111/j.1540-8175.2006.00342.x

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