Why the study?
Does the addition of UACR, hsCRP, and NT-proBNP to standard risk scores improve cardiovascular risk prediction in healthy subjects and those with known cardiovascular disease or diabetes?
Population
Healthy subjects with a 10-year risk of cardiovascular death <5% based on HeartScore, and subjects with…
Comparison
Measurement of N-terminal pro brain natriuretic… vs Risk stratification based on HeartScore alone
Design
Cohort
Follow-up
10 years
Authors
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Biomarker combinations may refine risk stratification in select groups; leaves open whether they improve prediction beyond standard scores.
Does the addition of UACR, hsCRP, and NT-proBNP to standard risk scores improve cardiovascular risk prediction in healthy subjects and those with known cardiovascular disease or diabetes?
The addition of UACR, hsCRP, and NT-proBNP to standard risk assessment can identify significant subgroups of patients at higher cardiovascular risk who may benefit from intensified primary or secondary prevention.
Olsen et al. (2010) studied this question.
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