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A dinuclear zinc(II) complex with N,N,N′,N′-tetrakis[(2-pyridyl)methyl]-2-hydroxy-1,3-diaminopropane efficiently hydrolyses ApA [adenylyl(3′-5′)adenosine] at pH 7 and 50 °C; the complex can thus be regarded as a good artificial ribonuclease which effectively mimics enzyme active sites.
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Yashiro et al. (1995) studied this question.
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