Why the study?
Does progressive decrease of asleep systolic blood pressure reduce the risk of cardiovascular events in individuals with normotension to hypertension?
Does progressive decrease of asleep systolic blood pressure reduce the risk of cardiovascular events in individuals with normotension to hypertension?
Asleep systolic blood pressure is a stronger prognostic marker for cardiovascular events than awake or office blood pressure, and its reduction is associated with significantly lower cardiovascular risk.
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Attenuation of asleep SBP marks better event-free survival independent of office/awake BP; leaves open whether nocturnal BP lowering reduces events.
Hermida et al. (2018) studied this question.
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