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October 8, 2024Vestnik Moskovskogo universiteta Seria 16 BiologiaOpen Access

Structural basis and molecular mechanisms of Cl- transmembrane transport in cardiomyocytes

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Why the study?

Intracellular chlorine concentration, equilibrium potential, and chloride currents significantly influence myocardial electrophysiological properties, but the structural and molecular mechanisms of chloride transport complexes in the heart warrant comprehensive discussion.

Design

Review

Authors

YVY. A. VoroninaAKA. M. KarhovVKV. S. Kuzmin

Discussion

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Overview

Chloride conductances shape myocardial electrophysiology; leaves open clinical targeting in arrhythmias pending trials.

Structured PICO

P
Population
Cardiomyocytes (review of basic science literature)

This review provides a comprehensive overview of the molecular structures and regulatory mechanisms of chloride channels in cardiomyocytes, emphasizing their importance in cardiac electrophysiology.

Cite This Study

Voronina et al. (2024) studied this question.

synapsesocial.com/papers/6a7dd73571280c8641cdb07fhttps://doi.org/10.55959/msu0137-0952-16-79-2s-4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Structural Basis and Molecular Mechanisms of Cl– Transmembrane Transport in Cardiomyocytes2024 · 3 citations
  2. 2Chloride channels and transporters – role in the electrical activity of pacemaker and working myocardium2024 · 2 citations
  3. 3Chloride conductance pathways in heart1991 · 117 citations
  4. 4Anion Transport in Heart2000 · 216 citations
  5. 5Insights into the structure, distribution and function of the cardiac chloride channels1999 · 75 citations