Why the study?
Does enalapril maleate improve endothelial function and insulin sensitivity in untreated hypertensive patients?
Population
9 non-smoking, untreated hypertensive patients and 12 age-matched healthy subjects. Total n=21.
Comparison
Enalapril maleate 5-40 mg/day for six months vs Baseline values and healthy subjects
Design
Cohort
Follow-up
6 months
Authors
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Enalapril-associated gains in endothelial function and insulin sensitivity support further study; hypothesis-generating and should not yet change practice.
Does enalapril maleate improve endothelial function and insulin sensitivity in untreated hypertensive patients?
Enalapril treatment for six months significantly improves both endothelial function and insulin sensitivity in patients with essential hypertension.
Tezcan et al. (2003) studied this question.
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