Why the study?
Does enalapril compared to nitrendipine improve insulin sensitivity in patients with essential hypertension?
Population
20 patients with essential hypertension
Comparison
Enalapril 10 mg once daily for 4 weeks vs Nitrendipine 20 mg once daily for 4 weeks
Design
RCT, double-blind
Follow-up
4 weeks per treatment period
Authors
Loading...
No effect on insulin sensitivity with either agent; confirms metabolic neutrality of enalapril and nitrendipine beyond BP reduction.
Does enalapril compared to nitrendipine improve insulin sensitivity in patients with essential hypertension?
In patients with essential hypertension, neither enalapril nor nitrendipine significantly altered insulin sensitivity despite comparable reductions in blood pressure.
Heise et al. (1999) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: