May 1, 1981HypertensionOpen Access

Abnormal baroreflex control of heart rate in prehypertensive and hypertensive Dahl genetically salt-sensitive rats.

View Full Paper

Ask AI

Bookmark

Population

Conscious sensitive (S) and resistant (R) Dahl rats

Comparison

High or low salt diet, phenylephrine… vs Resistant (R) Dahl rats

Design

Preclinical

Authors

Discussion

Neurogenic baroreflex impairment may initiate salt hypertension in Dahl rats; leaves open translation to human disease.

Population

Conscious sensitive (S) and resistant (R) Dahl rats

Intervention

High or low salt diet, phenylephrine administration, and ganglionic blockade

Comparator

Resistant (R) Dahl rats

Outcome

Sensitivity of baroreflex control of heart ratesurrogate

Impaired baroreflex function and neurogenic mechanisms contribute to the early stages of salt-induced hypertension in the Dahl rat model.

Gordon et al. (1981) studied this question.

View Full Paper

Ask AI

Bookmark