Why the study?
Does a high-salt diet exacerbate central baroreflex impairment in hypertension-sensitive Dahl rats?
Population
Hypertension-sensitive (DS) and hypertension-resistant (DR) Dahl rats
Comparison
High-salt diet for 7 weeks vs Low-salt diet for 7 weeks
Design
Preclinical
Follow-up
7 weeks
Authors
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High-salt may centrally worsen baroreflex impairment in salt-sensitive hypertension; extends animal data but leaves clinical translation open.
Does a high-salt diet exacerbate central baroreflex impairment in hypertension-sensitive Dahl rats?
High-salt diets may aggravate baroreflex impairment in hypertensive Dahl rats, at least in part, by acting centrally.
Miyajima et al. (1987) studied this question.
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