Regulatory Light Chain-a Myosin Kinase (aMK) Catalyzes Phosphorylation of Smooth Muscle Myosin Heavy Chains of Scallop, Patinopecten yessoensis

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Population

Myosin isolated from the opaque portion of scallop smooth muscle (Patinopecten yessoensis)

Design

Preclinical

Authors

Discussion

Findings remain preclinical; leaves open aMK's role in vertebrate myosin regulation.

Population

Myosin isolated from the opaque portion of scallop smooth muscle (Patinopecten yessoensis)

Intervention

Incubation with regulatory light chain-a myosin kinase (aMK) in the presence of [gamma-32P]ATP

Outcome

Phosphorylation of myosin heavy chains and its effect on ATPase activitysurrogate

Regulatory light chain-a myosin kinase (aMK) phosphorylates scallop smooth muscle myosin heavy chains, significantly decreasing its ATPase activity.

Sohma et al. (1988) studied this question.

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