February 1, 1985The Journal of Biochemistry

Calcium Binding and Conformation of Regulatory Light Chains of Smooth Muscle Myosin of Scallop1

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Population

Regulatory light chains (RLC-a and RLC-b) of smooth muscle myosin of scallop

Comparison

Calcium binding and tryptic digestion vs Regulatory light chain of striated muscle myosin…

Design

Preclinical

Authors

FMFumi MoritaHokkaido University of Science SKShuhei KondoNagoya City University KTKen TOMARIHokkaido University

Discussion

Member takes

Implication

Offers preliminary data on myosin light chain properties; leaves open extension to mammalian cardiac regulation.

Structured PICO

Population

Regulatory light chains (RLC-a and RLC-b) of smooth muscle myosin of scallop

Intervention

Calcium binding and tryptic digestion

Comparator

Regulatory light chain of striated muscle myosin of scallop (RLC-st) and other Ca2+ binding proteins (parvalbumin, calmodulin)

Outcome

Calcium binding properties (dissociation constant, molar absorption coefficient) and conformational changes (NMR, CD spectra, tryptic digestion susceptibility)surrogate

The study characterizes the calcium binding and conformational properties of scallop smooth muscle myosin regulatory light chains, suggesting domain 4 folds near the calcium binding site of domain 1.

Cite This Study

Morita et al. (1985) studied this question.

synapsesocial.com/papers/6a872286713eb98b40ca2a0f https://doi.org/10.1093/oxfordjournals.jbchem.a135090

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Calcium Binding and Conformation of Regulatory Light Chains of Smooth Muscle Myosin of Scallop1

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Calcium Binding and Conformation of Regulatory Light Chains of Smooth Muscle Myosin of Scallop1

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider