Why the study?
Patients with cancer are at risk of developing arterial thromboembolism, but data on the association of potential blood-based biomarkers with this risk are scarce.
Are elevated complete blood count parameters, d-dimer, and soluble P-selectin levels associated with an increased risk of arterial thromboembolism in patients with cancer?
Population
1883 patients with newly diagnosed cancer or progressive disease after complete or partial remission
Comparison
Baseline complete blood count parameters, total cholesterol, d-dimer, and sP-selectin levels
Design
Cohort study
Follow-up
2 years
Authors
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May aid ATE risk assessment in cancer; hypothesis-generating and requires prospective validation before clinical use.
Are elevated complete blood count parameters, d-dimer, and soluble P-selectin levels associated with an increased risk of arterial thromboembolism in patients with cancer?
Elevated absolute neutrophil count and higher sP-selectin levels are associated with an increased risk of arterial thromboembolism in patients with cancer.
Grilz et al. (2019) studied this question.
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