Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
January 19, 2007HeartOpen Access

Heart rate and microinflammation in men: a relevant atherothrombotic link

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Is increased resting heart rate associated with a microinflammatory response in men?

Population

4,553 apparently healthy men and those with atherothrombotic risk factors

Comparison

High resting heart rate vs Low resting heart rate

Design

Cohort

Authors

OROri RogowskiTel Aviv UniversityISI ShapiraTel Aviv UniversityASArie ShiromTel Aviv University

Discussion

Loading...

Member takes

Implication

Higher resting HR associates with elevated inflammatory markers in men; hypothesis-generating for atherothrombotic links and requires prospective confirmation.

Structured PICO

Is increased resting heart rate associated with a microinflammatory response in men?

P
Population
4,553 apparently healthy men and those with atherothrombotic risk factors
I
Intervention
High resting heart rate (fifth quintile ≥79 beats/min)
C
Comparator
Low resting heart rate (first quintile ≤58 beats/min)
O
Outcome
Concentrations of inflammatory biomarkers (fibrinogen, high-sensitivity C-reactive protein, and absolute number of polymorphonuclear leucocytes)surrogate

Increased resting heart rate is associated with elevated inflammatory biomarkers in men, suggesting a potential atherothrombotic link.

Cite This Study

Rogowski et al. (2007) studied this question.

synapsesocial.com/papers/6a7e22f44bd90feed65d79c8https://doi.org/10.1136/hrt.2006.101949
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Influence of Heart Rate on Mortality in a French Population1999 · 359 citations
  2. 2Acute-Phase Proteins and Other Systemic Responses to Inflammation1999 · 6,806 citations
  3. 3CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease2004 · 178 citations
  4. 4Alterations in platelet function during the ovarian cycle2002 · 50 citations