Recombinant hnRNP protein A1 and its N-terminal domain show preferential affinity for oligodeoxynucleotides homologous to intron/exon acceptor sites

In vitro minimal system using purified recombinant human hnRNP protein A1 (expressed in bacteria) and synthetic oligodeoxynucleotides (21-mers)

Binding assay with synthetic oligodeoxynucleotides corresponding to the 3'-splice site of IVS1 of human beta-globin pre-mRNA and of IVS1 of Adenovirus type 2 major late transcript, including mutation studies and truncated recombinant protein

Binding preference/affinity of protein A1 to oligodeoxynucleotide sequencessurrogate