Why the study?
Does atrial natriuretic factor infusion attenuate the pulmonary pressor response to hypoxia in anesthetized pigs?
Population
Anesthetized pigs (n=14 for hypoxia correlation, n=7 for ANF infusion)
Comparison
Atrial natriuretic factor infusion at 0.01… vs Normoxic animals receiving ANF infusion
Design
Preclinical
Authors
Loading...
ANF modulates hypoxic pulmonary responses in pigs; leaves open therapeutic translation to human pulmonary hypertension.
Does atrial natriuretic factor infusion attenuate the pulmonary pressor response to hypoxia in anesthetized pigs?
Atrial natriuretic factor acts as an endogenous pulmonary vasodilator that attenuates the pulmonary pressor response to hypoxia in a porcine model.
Adnot et al. (1988) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: