What question did this study set out to answer?

Determine the effect of exercise training on plasma catecholamines and cardiovascular hemodynamics at rest, during submaximal exercise, and under orthostatic stress in hypertensive adolescents.

April 1, 1984Clinical Physiology

Effect of exercise training on plasma catecholamines and haemodynamics of adolescent hypertensives during rest, submaximal exercise and orthostatic stress

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Why the study?

Does exercise training improve blood pressure and haemodynamics in adolescents with essential hypertension?

Population

12 adolescents with essential hypertension

Comparison

Exercise training vs Pre-training baseline

Design

Cohort

Authors

JHJames M. HagbergUniversity of Maryland, College Park DGDavid GoldringSt. Louis Children's Hospital GHGregory W. HeathUniversity of Tennessee at Chattanooga

Discussion

Member takes

Implication

Supports exercise for BP reduction in hypertensive adolescents independent of catecholamines; hypothesis-generating and requires RCT confirmation.

Key Points

Determine the effect of exercise training on plasma catecholamines and cardiovascular hemodynamics at rest, during submaximal exercise, and under orthostatic stress in hypertensive adolescents.
Assessed 12 adolescents with essential hypertension before and after an exercise training program (N=12).
Measured maximal oxygen consumption (VO2max), body composition, blood pressure, heart rate, and plasma norepinephrine and epinephrine across resting, standing, and submaximal exercise conditions.
Maximal oxygen consumption increased by 13% without changes in body weight or body fat, while resting systolic and diastolic blood pressure decreased significantly despite unchanged resting plasma catecholamine concentrations.
Post-training systolic blood pressure increases during standing orthostatic stress were significantly lower, and both blood pressure and catecholamine levels were significantly reduced at identical absolute workloads.
Blood pressure responses at identical relative workloads remained unchanged post-training despite significantly higher plasma norepinephrine levels.

Structured PICO

Does exercise training improve blood pressure and haemodynamics in adolescents with essential hypertension?

Population

12 adolescents with essential hypertension

Intervention

Exercise training

Comparator

Pre-training baseline

Outcome

Plasma catecholamine concentrations, blood pressure and cardiovascular haemodynamics at rest and during submaximal exercise and orthostatic stresssurrogate

Exercise training in adolescent hypertensives lowers resting blood pressure and improves hemodynamic responses to stress, but these effects are not mediated by reductions in plasma catecholamines.

Cite This Study

Hagberg et al. (1984) studied this question.

synapsesocial.com/papers/6a7e76df8129fc77b4b29f9d https://doi.org/10.1111/j.1475-097x.1984.tb00227.x

Topics

Hypertension management

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Implication

Supports exercise for BP reduction in hypertensive adolescents independent of catecholamines; hypothesis-generating and requires RCT confirmation.

Effect of exercise training on plasma catecholamines and haemodynamics of adolescent hypertensives during rest, submaximal exercise and orthostatic stress

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Effect of exercise training on plasma catecholamines and haemodynamics of adolescent hypertensives during rest, submaximal exercise and orthostatic stress

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider