Population
1 elderly woman receiving long-term oral anticoagulant therapy, with coinciding periods of congestive…
Design
Case_report
Authors
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May warrant INR vigilance in CHF patients on coumarins; hypothesis-generating for acquired protein C deficiency in skin necrosis.
Repeated periods of congestive heart failure may contribute to coumarin-induced skin necrosis due to an acquired functional protein C deficiency and extreme hypocoagulability.
Robert G. C. Teepe (1986) studied this question.
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