Population
Cultured rat thoracic aortic smooth-muscle (RTASM) cells
Comparison
Pretreatment with chloroquine, dinitrophenol, or… vs Control cells
Design
Preclinical
Follow-up
up to 60 minutes
Authors
Loading...
Indicates ANF receptor down-regulation in animal vascular cells; leaves open relevance to human physiology or therapy.
ANF induces down-regulation of its receptor in vascular smooth muscle cells primarily through increased internalization and metabolic degradation of the ligand-receptor complex.
Kailash N. Pandey (1992) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: