Population
Strips of frog ventricular muscle (width less than or equal to 8 mm)
Design
Preclinical
Authors
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Leaves open the role of sodium-independent calcium efflux in cardiac muscle; no clinical implications from this animal study.
The study suggests that intracellular calcium during sodium-lack contracture plateau is a steady-state value dependent on sodium-dependent influx and sodium-independent efflux/uptake mechanisms.
Neal Shepherd (1986) studied this question.
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