Population
Frog atrial fibres
Comparison
Variation of extracellular calcium and sodium… vs Normal [Ca]o and [Na]o concentrations
Design
Preclinical
Authors
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Supports Na/Ca exchange in amphibian heart; leaves open its role in human Ca handling or therapies.
This preclinical study provides evidence for a calcium-sodium exchange mechanism in frog atrial fibres where one calcium ion is exchanged for two sodium ions.
Benninger et al. (1976) studied this question.
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