Population
Isolated guinea pig ventricular myocytes loaded with sodium-binding benzofuran isophthalate (SBFI) and fluo 3
Comparison
30 min perfusion of K-free solution (with or… vs Control state (prior to perfusion)
Design
Preclinical
Follow-up
30 min
Authors
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Novel dual-fluorescence method enables simultaneous myocyte Na+ and Ca2+ imaging; leaves open in vivo relevance of Na+-Ca2+ exchange during K+ depletion.
A novel dual-fluorescence method enables simultaneous measurement of intracellular Na+ and Ca2+ in isolated myocytes, revealing the role of Na+-Ca2+ exchange during K+-free perfusion.
Hayashi et al. (1994) studied this question.
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