Why the study?
Does bilateral renal denervation affect sodium balance, the renin-angiotensin system, and systemic blood pressure in unrestrained conscious rats?
Does bilateral renal denervation affect sodium balance, the renin-angiotensin system, and systemic blood pressure in unrestrained conscious rats?
Bilateral renal denervation in conscious rats lowers blood pressure and plasma renin concentration but does not impair the ability to maintain positive sodium balance on a low-sodium diet.
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Renal denervation lowers BP and renin without impairing sodium balance in conscious rats; leaves open clinical translation.
Fernández–Repollet et al. (1985) studied this question.
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