Why the study?
Do long-term survivors of childhood brain cancer have an increased risk of cardiovascular disease compared to healthy controls?
Population
55 participants, comprising 26 long-term survivors of childhood brain cancer and 29 healthy controls.
Comparison
History of childhood brain cancer and its… vs Healthy controls
Design
Case-control
Follow-up
mean 16 years posttreatment
Authors
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Supports enhanced CVD risk assessment in survivors; leaves open whether markers predict events or warrant intervention.
Do long-term survivors of childhood brain cancer have an increased risk of cardiovascular disease compared to healthy controls?
Long-term survivors of childhood brain cancer have an increased risk for cardiovascular disease driven by dyslipidemia, central obesity, and elevated blood pressure, particularly those with growth hormone deficiency.
Heikens et al. (2000) studied this question.
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