BNP level predicts bleeding event in patients with heart failure after percutaneous coronary intervention

Figures

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  Figure 1. Kaplan-Meier estimates of bleeding events (GUSTO severe/moderate) between non-HF groups and the HF groups classified according to BNP, EF level, ischaemic aetiology. Kaplan-Meier curves show the rate of major bleeding events after PCI according to HF and severity (BNP and EF level). The bleeding event rate was significantly higher in the HF with high BNP level group than in the non-HF group. There was no difference in the rate of major bleeding events among patients with HF, regardless of the EF. BNP, brain natriuretic peptide; EF, ejection fraction; GUSTO, Global Use of Streptokinase and t-PA for Occluded Coronary Arteries; HF, heart failure; PCI, percutaneous coronary intervention.

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  Figure 2. Kaplan-Meier estimates of MACE and all-cause death. Kaplan-Meier curves show the rates of MACE and all-cause death after PCI according to HF and severity (BNP level). The MACE and all-cause rates were significantly higher in the HF with high BNP level group than in the other groups. BNP, brain natriuretic peptide; HF, heart failure; MACE, major adverse cardiac events; PCI, percutaneous coronary intervention.

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  Figure 3. Total Thrombus-Formation Analysis System level in patients with and without HF and patients with HF with high BNP levels, HF with low BNP levels and without HF. Upper box plot shows the level of PL-AUC in patients with and without HF and patients according to HF and severity (BNP level). Lower box plot shows the level of AR-AUC in patients with and without HF and patients according to HF and severity (BNP level). AR, atheroma chip; AUC, area under the curve; BNP, B-type natriuretic peptide; HF, heart failure; PL, platelet chip.