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Distal coronary artery hyperemic responses measured with ultrasound Doppler-tipped guidewires provide new insights into coronary physiology and vasodilatory reserve.
Basal patterns (systolic/diastolic components) of coronary flow velocity as previously described are generally maintained during hyperemia and can be easily recorded in the catheterization laboratory during pharmacologic stimulation. The interpretation of the clinical significance of coronary vasodilatory reserve may be complicated by both coronary and myocardial diseases. Distal coronary artery hyperemic responses measured with ultrasound Doppler-tipped guidewires will provide new information on traditional observations of coronary physiology in humans.
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Kern et al. (1992) studied this question.
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