Key result
Preprocedural coronary angiography guidance for CRT implantation significantly reduced total implantation time (53 vs 66 minutes, P<.0001) compared to standard CRT without guidance.
Why the study?
The study was designed to examine the usefulness of preprocedural coronary venous system imaging using conventional coronary angiography before cardiac resynchronization therapy implantation.
Does preprocedural coronary angiography guidance reduce implantation time, fluoroscopy time, contrast use, and radiation exposure in patients undergoing CRT implantation?
RCT (n=180)
1:2
Does preprocedural coronary angiography guidance reduce implantation time, fluoroscopy time, contrast use, and radiation exposure in patients undergoing CRT implantation?
Performing preprocedural coronary angiography to image the coronary venous system before CRT implantation significantly simplifies the procedure by reducing implantation time, fluoroscopy time, contrast volume, and radiation exposure.
Should not yet change CRT implant practice; leaves open whether preprocedural angiography guidance warrants routine use.
Cardiac resynchronization therapy (CRT) is a treatment modality for selected patients with refractory heart failure. We intended to examine the usefulness of coronary venous system imagining with conventional coronary angiogram before the CRT implantation procedure. A total of 180 patients were scheduled for CRT and were prospectively randomized 1:2 into 2 groups. Group 1 (n = 60) received standard CRT procedure without the guidance of selective left coronary angiography. In group 2 (n = 120), CRT implantation was accomplished with the guidance of the preprocedural coronary angiography. We compared the 2 groups in terms of the total implantation time, total fluoroscopy time, the amount of contrast medium used, and cumulative radiation exposure. The total implantation and fluoroscopy times, the amount of contrast medium used, and cumulative radiation exposure were significantly less in group 2 compared with group 1 (53 ± 7 vs 66 ± 9 minutes, 11 ± 3 vs 20 ± 5 minutes, 24 ± 8 vs 42 ± 14 mL, 26 192 ± 6658 vs 37 388± 9064 mGy cm 2 , and 253 ± 49 vs 392 ± 79 mGy, P < .0001, respectively). We concluded that coronary angiography prior to CRT implantation is useful in simplifying the procedure, saving time, reducing radiation exposure, and reducing contrast use.
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Polat et al. (2021) conducted an RCT in refractory heart failure (n=180). Preprocedural coronary angiography guidance vs. Standard CRT procedure without selective left coronary angiography guidance was evaluated on Total implantation time (minutes) (p=<.0001). Preprocedural coronary angiography guidance for CRT implantation significantly reduced total implantation time (53 vs 66 minutes, P<.0001) compared to standard CRT without guidance.
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